1.北京中医药大学第二临床医学院,北京市 100078
2.中国中医科学院广安门医院,北京市 100053
3.成都中医药大学基础医学院,成都 611130
4.成都中医药大学临床医学院,成都 610032
龚进,男,25岁,硕士。研究方向:中医药防治肾脏疾病。
王暴魁,E-mail:wbk03311@sina.com
收稿:2024-09-03,
纸质出版:2025-10-25
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龚进,陈易瑶,任雪雷,等.基于“因加而发”理论的特发性膜性肾病中医证治探讨[J].北京中医药,2025,44(10):1351-1354.
GONG Jin,CHEN Yiyao,REN Xuelei,et al.Traditional Chinese medicine syndrome differentiation and treatment of idiopathic membranous nephropathy based on the theory of "caused by additions"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1351-1354.
龚进,陈易瑶,任雪雷,等.基于“因加而发”理论的特发性膜性肾病中医证治探讨[J].北京中医药,2025,44(10):1351-1354. DOI: 10.16025/j.1674-1307.2025.10.025.
GONG Jin,CHEN Yiyao,REN Xuelei,et al.Traditional Chinese medicine syndrome differentiation and treatment of idiopathic membranous nephropathy based on the theory of "caused by additions"[J]. Beijing Journal of Traditional Chinese Medicine,2025,44(10):1351-1354. DOI: 10.16025/j.1674-1307.2025.10.025.
“因加而发”指既往故邪和新感之邪合而致病,后世医家在此基础上延伸出合邪致病、伏邪致病、多因致病等理论,强调了发病过程中的整体观念及动态性。目前特发性膜性肾病(IMN)的发病机制尚未完全清楚,其与先天遗传、后天环境等因素密切相关,且常因外部感染导致病情加重或反复,上述特质与“因加而发”强调多因素叠加而致病的内涵一致。基于“因加而发”理论分析IMN发病,包含正虚和邪盛两个方面,且通常为多种邪气杂合以致病。治疗强调外风宜散、内风宜疏,健脾补肾、扶正助元,活血化瘀,除湿解毒,清热利咽。
The concept of "caused by additions" refers to the combined effect of pre-existing pathogenic factors and new infections that lead to disease. Subsequent generations of physicians expanded this idea to include theories such as combined pathogenic factors, latent pathogenic factors, and multiple causes of disease, emphasizing a holistic and dynamic view of the onset of illness. The pathogenesis of idiopathic membranous nephropathy (IMN) remains incompletely understood, but it is closely related to factors such as genetic predisposition and environmental influences. External infections often worsen or trigger relapses of the condition, which aligns with the essence of "caused by additions", emphasizing the accumulation of multiple factors leading to disease. Based on the "caused by additions" theory, the pathogenesis of IMN involves two main aspects: deficiency of healthy
qi
and excess of pathogenic factors, often resulting from a combination of multiple pathogenic factors. Treatment focuses on dispersing external wind and relieving internal wind, strengthening the spleen and tonifying the kidneys to support healthy
qi
and reinforce vitality, activating blood circulation and resolving stasis, eliminating dampness and removing toxins, and clearing heat and soothing the throat.
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