基于“气脉常通”辨治泛血管疾病经验初探

皮庆敏; 李思耐; 张振民; 尚菊菊

doi:10.16025/j.1674-1307.2026.03.024

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基于“气脉常通”辨治泛血管疾病经验初探

学术探讨 | 更新时间：2026-06-02

- 基于“气脉常通”辨治泛血管疾病经验初探
- Differentiation and treatment of pan-vascular diseases based on the theory of "qi-pulse continuity"
- 北京中医药 2026年45卷第3期页码：416-420
- 作者机构：
  
  1.北京中医药大学，北京 100029
  2.北京市中医药研究所，北京 100010
  3.首都医科大学附属北京中医医院心血管科，北京 100010
- 作者简介：
  
  皮庆敏，女，24岁，硕士研究生。研究方向：中西医结合防治心血管疾病。
  尚菊菊，E-mail：shangjuju@bjzhongyi.com
- 基金信息：
  
  首都卫生发展科研专项(首发2024-2-2236)
- DOI：10.16025/j.1674-1307.2026.03.024
  中图分类号：
- 收稿：2024-11-17，
  
  纸质出版：2026-03-25
- 稿件说明：
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皮庆敏，李思耐，张振民，等.基于“气脉常通”辨治泛血管疾病经验初探［J］.北京中医药，2026，45（3）：416-420.

PI Qingmin,LI Sinai,ZHANG Zhenmin,et al.Differentiation and treatment of pan-vascular diseases based on the theory of "qi-pulse continuity"[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(03):416-420.
皮庆敏，李思耐，张振民，等.基于“气脉常通”辨治泛血管疾病经验初探［J］.北京中医药，2026，45（3）：416-420. DOI： 10.16025/j.1674-1307.2026.03.024.

PI Qingmin,LI Sinai,ZHANG Zhenmin,et al.Differentiation and treatment of pan-vascular diseases based on the theory of "qi-pulse continuity"[J]. Beijing Journal of Traditional Chinese Medicine,2026,45(03):416-420. DOI： 10.16025/j.1674-1307.2026.03.024.

摘要

泛血管疾病是一类涉及多个血管床的系统性血管病变，痰浊瘀血互结是泛血管疾病的关键病理改变，而痰浊瘀血等病理产物的形成与气脉常通失调密切相关。基于“气脉常通”观点，气血运行失司是泛血管疾病的核心病机，脉道不荣、痰浊壅脉、痰瘀结脉、血脉闭阻、邪犯血脉引发内皮功能障碍、脂质代谢紊乱、氧化应激、炎症反应、血管重构等病理变化，故应以“气脉常通”为泛血管疾病的治疗目标，并拟定化痰逐瘀治其标、调和气血治其本的临床治疗策略。

Abstract

Pan-vascular diseases are a group of systemic vascular disorders involving multiple vascular beds， and their pathological mechanisms have not yet been fully elucidated. Clinical management emphasizes a multidisciplinary and multisystem comprehensive approach to prevention and treatment， which is highly consistent with the holistic view and syndrome differentiation-based treatment of traditional Chinese medicine （TCM）. The mutual binding of phlegm turbidity and blood stasis represents a key pathological change in pan-vascular diseases， and the for

mation of such pathological products is closely associated with dysregulation of "

-pulse continuity". Based on the theory of "

-pulse continuity"， and taking the disordered circulation of

and blood as the starting point， this article analyzes the mechanism of atherosclerosis：the core pathological basis of pan-vascular diseases，from a TCM perspective. It discusses the role of

and blood disharmony in pathological processes including endothelial dysfunction， lipid metabolism disorder， oxidative stress， inflammatory response， and vascular remodeling， from the perspectives of impaired vascular nourishment， phlegm turbidity obstructing the vessels， phlegm-stasis binding within the vessels， vascular obstruction， and invasion of pathogenic factors into the vessels. On this basis， a therapeutic strategy for pan-vascular diseases targeting the maintenance of "

-pulse continuity" is proposed， providing a reference for clinical treatment of pan-vascular diseases.

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references

杨靖 , 张英梅 , 葛均波 . 泛血管疾病防控:从疾病治疗到综合管理 [J ] . 中华心血管病杂志(网络版) , 2021 , 4 ( 1 ): 1 - 6 .

彭彬 , 王猛 , 马思佳 , 等 . 基于“气脉常通”论治慢性疲劳综合征 [J ] . 中国中医药信息杂志 , 2024 , 31 ( 10 ): 176 - 180 .

杨关林 , 张哲 , 张会永 , 等 . 血脉病探要 [J ] . 辽宁中医杂志 , 2007 , 31 ( 11 ): 1528 - 1529 .

张思祥 , 刘政 , 赵友民 , 等 . 基于“虚气留滞”理论探讨泛血管疾病的发病机制 [J ] . 北京中医药大学学报 , 2024 , 47 ( 7 ): 983 - 988 .

柴艺汇 , 陈雨佳 , 陈波洋 , 等 . 泛血管疾病“虚毒瘀”病机中西医结合理论探析 [J ] . 贵州中医药大学学报 , 2022 , 44 ( 6 ): 32 - 36 .

申鑫惠 , 杨宇峰 , 余丞浩 , 等 . 从阴火病络视角探讨泛血管疾病的发病机制 [J ] . 北京中医药大学学报 , 2023 , 46 ( 9 ): 1296 - 1300 .

李捷 , 郑雅峰 , 庄欣 , 等 . 基于“伏邪阻络”理论探讨中医药防治2型糖尿病泛血管病变的内涵 [J ] . 北京中医药 , 2025 , 44 ( 1 ): 114 - 117 .

SPINELLI JB , HAIGIS MC . The multifaceted contributions of mitochondria to cellular metabolism [J ] . Nature Cell Biology , 2018 , 20 ( 7 ): 745 - 754 ．

林飞 , 郭丽丽 , 王阶 . 基于线粒体的功能阐释中医“气”的作用 [J ] . 中国中西医结合杂志 , 2014 , 34 ( 8 ): 903 - 906 .

MEYER A , LAVERNY G , BERNARDI L , et al . Mitochondria:an organelle of bacterial origin controlling inflammation [J ] . Front Immunol , 2018 , 9 : 536 .

杨泽 , 陈佳丽 , 汪翔 , 等 . 清浊相干理论探微 [J ] . 新中医 , 2021 , 53 ( 17 ): 202 - 205 .

GOLDSTEIN JL , BROWN MS . A century of cholesterol and coronaries:from plaques to genes to statins [J ] . Cell , 2015 , 161 ( 1 ): 161 - 172 .

程英锐 . 论痰气相关 [J ] . 光明中医 , 2010 , 25 ( 4 ): 691 .

津液代谢肺脾肾与水通道蛋白关系的研究 [D ] . 广州 : 广州中医药大学 , 2012 .

YUN X , JIANG H , LAI N , et al . Aquaporin 1-mediated changes in pulmonary arterial smooth muscle cell migration and proliferation involve β-catenin [J ] . Am J Physiol Lung Cell Mol Physiol , 2017 , 313 ( 5 ): L889 - L898 .

NEWBY A . Fibrous cap formation or destruction：the critical importance of vascular smooth muscle cell proliferation， migration and matrix formation [J ] . Cardiovascular Research ， 1999 ： 345 - 360 .

李文京 , 王革生 , 郭蓉娟 . 基于“阳化气，阴成形”理论探讨动脉粥样硬化的防治思路 [J ] . 北京中医药 , 2024 , 43 ( 10 ): 1185 - 1188 .

CHISTIAKOV DA , MELNICHENKO AA , MYASOEDOVA VA , et al . Mechanisms of foam cell formation in atherosclerosis [J ] . J Mol Med(Berl) , 2017 , 95 ( 11 ): 1153 - 1165 .

PENG J , LUO F , RUAN G , et al . Hypertriglyceridemia and atherosclerosis [J ] . Lipids Health Dis , 2017 , 16 ( 1 ): 233 .

GROENEN AG , HALMOS B , TALL AR , et al . Cholesterol efflux pathways, inflammation, and atherosclerosis [J ] . Crit Rev Biochem Mol Biol , 2021 , 56 ( 4 ): 426 - 439 .

DONG LH , WEN JK , LIU G , et al . Blockade of the Ras-extracellular signal-regulated kinase 1/2 pathway is involved in smooth muscle22 alpha-mediated suppression of vascular smooth muscle cell proliferation and neointima hyperplasia [J ] . Arterioscler Thromb Vasc Biol , 2010 , 30 ( 4 ): 683 - 691

TIEU BC , JU X , LEE C , et al . Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodeling [J ] . J Vasc Res , 2011 , 48 ( 3 ): 261 - 272

WANG X , KHALIL RA . Matrix metalloproteinases,vascular remodeling,and vascular disease [J ] . Adv Pharmacol , 2018 , 81 : 241 - 330

张伟 , 邓常清 . 从气血理论探讨病理性血管重构的研究思路 [J ] . 中华中医药杂志 , 2019 , 34 ( 10 ): 4713 - 4717 .

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