Observation on therapeutic effect of Yaoshi Granules as an adjuvant treatment of metabolic syndrome based on the method of relieving depression and clearing heat

WANG Fan; NI Qing; AN Ran; ZHANG Qiu-ju; WU Rui; XU Hong-liang

doi:10.16025/j.1674-1307.2021.03.024

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Observation on therapeutic effect of Yaoshi Granules as an adjuvant treatment of metabolic syndrome based on the method of relieving depression and clearing heat

更新时间：2023-04-10

- Observation on therapeutic effect of Yaoshi Granules as an adjuvant treatment of metabolic syndrome based on the method of relieving depression and clearing heat
- Beijing Journal of Traditional Chinese Medicine Vol. 40, Issue 3, Pages: 300-303(2021)
- 作者机构：
  
  1. 中国中医科学院广安门医院南区内分泌科
  2. 中国中医科学院广安门医院内分泌科
- 作者简介：
- 基金信息：
- DOI：10.16025/j.1674-1307.2021.03.024
  CLC：
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[1]王凡,倪青,安然,张秋菊,吴瑞,许宏亮.基于开郁清热法的药食颗粒辅助治疗代谢综合征疗效观察[J].北京中医药,2021,40(03):300-303.

WANG Fan, NI Qing, AN Ran, et al. Observation on therapeutic effect of Yaoshi Granules as an adjuvant treatment of metabolic syndrome based on the method of relieving depression and clearing heat. [J]. Beijing Journal of Traditional Chinese Medicine 40(3):300-303(2021)
[1]王凡,倪青,安然,张秋菊,吴瑞,许宏亮.基于开郁清热法的药食颗粒辅助治疗代谢综合征疗效观察[J].北京中医药,2021,40(03):300-303. DOI： 10.16025/j.1674-1307.2021.03.024.

WANG Fan, NI Qing, AN Ran, et al. Observation on therapeutic effect of Yaoshi Granules as an adjuvant treatment of metabolic syndrome based on the method of relieving depression and clearing heat. [J]. Beijing Journal of Traditional Chinese Medicine 40(3):300-303(2021) DOI： 10.16025/j.1674-1307.2021.03.024.

摘要

目的观察基于开郁清热法的药食颗粒辅助治疗代谢综合征（MS）的临床疗效。方法选择2017年7月—2018年6月于中国中医科学院广安门医院南区内分泌科就诊的MS患者45例,按照随机数字表将患者分为对照组和治疗1、2组,各15例。对照组给予MS规范治疗,即生活方式干预+常规药物治疗;治疗1组在对照组治疗基础上,加用水溶性膳食纤维;治疗2组在对照组治疗基础上,加用水溶性膳食纤维及药食颗粒。比较治疗12周后3组理化指标疗效及生活质量改善效果,对比治疗前后各组理化指标变化。结果治疗12周后,治疗1组、治疗2组理化指标改善总有效率均高于对照组,但差异无统计学意义（P>0.05）;治疗2组显效率高于治疗1组及对照组（P<0.05）。治疗1组、治疗2组的生活质量改善总有效率均高于对照组（P<0.05）;且治疗2组显效率高于治疗1组及对照组（P<0.05）。治疗12周后3组BMI、FPG、2 h PG、TG均较治疗前降低（P<0.05）,HDL-C较治疗前升高（P<0.05）;治疗后治疗1组、治疗2组以上指标改善程度优于对照组（P<0.05）,但治疗后治疗1组、治疗2组的以上指标比较差异并无统计学意义（P>0.05）。结论基于开郁清热法的药食颗粒辅助治疗MS可提高疗效,改善患者生活质量。

Abstract

关键词

代谢综合征药食同源开郁清热法膳食纤维药食颗粒

Keywords

代谢综合征药食同源开郁清热法膳食纤维药食颗粒

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