1.邯郸市中医院骨伤科,邯郸 056001
2.河北省中医药发展中心,石家庄 050051
蒿俊行,男,36岁,硕士,主治医师。研究方向:创伤骨科及关节外科。
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蒿俊行,王拴虎,张恒云,等.加味当归补血汤对高龄股骨粗隆间骨折患者失血量及骨折愈合的影响[J].北京中医药,2022,41(5):558-561.
HAO Jun-hang,WANG Shuan-hu,ZHANG Heng-yun,et al.Effect of modified Danggui Buxue Decoction on blood loss and fracture healing in elderly patients with intertrochanteric fractures[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(05):558-561.
蒿俊行,王拴虎,张恒云,等.加味当归补血汤对高龄股骨粗隆间骨折患者失血量及骨折愈合的影响[J].北京中医药,2022,41(5):558-561. DOI: 10.16025/j.1674-1307.2022.05.024.
HAO Jun-hang,WANG Shuan-hu,ZHANG Heng-yun,et al.Effect of modified Danggui Buxue Decoction on blood loss and fracture healing in elderly patients with intertrochanteric fractures[J]. Beijing Journal of Traditional Chinese Medicine,2022,41(05):558-561. DOI: 10.16025/j.1674-1307.2022.05.024.
目的,2,研究加味当归补血汤对接受股骨近端防旋髓内钉(PFNA)治疗的高龄股骨粗隆间骨折患者围手术期失血量及骨折愈合的影响。,方法,2,将单侧股骨粗隆间骨折高龄患者60例随机分为治疗组和对照组,每组30例。2组均采用闭合复位PFNA治疗,治疗组在此基础上配合加味当归补血汤口服治疗,对照组仅予安慰剂口服,均于术前2 d开始服用至术后14 d。观察2组术中显性失血量、术中至术后48 h隐性失血量、骨折愈合时间、髋关节功能。,结果,2,治疗组患者术中显性失血量、术中至术后48 h隐性失血量分别为(176.07±48.45)mL、(335.07±63.17)mL,对照组分别为(214.80±14.18) mL、(414.60±93.50)mL,治疗组显性失血量及隐性失血量均少于对照组,差异均有统计学意义(,P,<,0.05);术后治疗组患者骨折愈合时间明显短于对照组(,P,<,0.05),且髋关节功能改善优于对照组(,P,<,0.05)。,结论,2,行PFNA治疗的高龄股骨粗隆间骨折患者,术前及术后服用加味当归补血汤可减少围手术期出血、促进骨折愈合、改善髋关节功能。
加味当归补血汤股骨粗隆间骨折骨不连隐性失血量髋关节功能
YOON YC, OH CW, SIM JA,et al. Intraoperative assessment of reduction quality during nail fixation of intertrochanteric fractures[J].Injury,2020,51(2):400-406.
ADAMS CI, ROBINSON CM, COURT-BROWN CM,et al. Prospective randomized controlled trial of an intramedullary nail versus dynamic screw and plate for intertrochanteric fractures of the femur[J].J Orthop Trauma,2001,15(6):394-400.
GUO Y,YANG HP,DOU QJ,et al. Efficacy of femoral nail anti-rotation of helical blade in unstable intertrochanteric fracture[J]. Eur Rev Med Pharmacol Sci,2017,21(3 Suppl):6-11.
SIMUNOVIC N, DEVEREAUX PJ, SPRAGUE S, et al. Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis[J]. CMAJ,2010,182(15):1609-1616.
MüLLER F, DOBLINGER M, KOTTMANN T,et al. PFNA and DHS for AO/OTA31-A2 fractures: radiographic measurements, morbidity and mortality[J].Eur J Trauma Emerg Surg,2020,46(5):947-953.
WANG WL, SHEU SY, CHEN YS,et al. Enhanced bone tissue regeneration by porous gelatin composites loaded with the Chinese herbal decoction danggui buxue tang[J]. PLoS One, 2015,10(6):e0131999.
RICHARD EB,CHRISTOPHER GM,THEERACHAI A.骨折治疗的AO原则[M].危杰,刘瑶,吴新宝,等译.3版.上海:上海科技出版社,2019:745-751.
李灿东.中医诊断学[M].10版.北京:中国中医药出版社,2016:237.
GROSS JB. Estimating allowable blood loss: corrected for dilution[J].Anesthesiology,1983,58(3):277-280.
LAU BC, SCRIBANI M, LASSITER T, et al. Correlation of single assessment numerical evaluation score for sport and activities of daily living to modified harris hip score and hip outcome score in patients undergoing arthroscopic hip surgery[J].Am J Sports Med,2019,47(11):2646-2650.
MATSUNAGA FT, TAMAOKI MJ, MATSUMOTO MH, et al. Minimally invasive osteosynthesis with a bridge plate versus a functional brace for humeral shaft fractures: a randomized controlled trial[J].J Bone Joint Surg Am,2017,99(7): 583–592.
陈孝平,汪建平,赵继宗,等.外科学[M].9 版.北京:人民卫生出版社,2018:618-619.
HAO Z, WANG X, ZHANG X. Comparing surgical interventions for intertrochanteric hip fracture by blood loss and operation time: a network meta-analysis[J].J Orthop Surg Res,2018,13(1):157.
秦颖达,李衡.老年股骨粗隆间骨折两种髓内固定比较[J].中国矫形外科杂志,2021,29(22):2017-2022.
YU X, ZHANG H, ZHANG X,et al. Effects of the ratios of marrow cavity diameter to intramedullary nail diameter from different layers on blood loss during perioperative period for femoral intertrochanteric fractures[J].Medicine (Baltimore), 2019,98(37):e16936.
吴喜见.当归补血汤辅治消化道出血临床观察[J].实用中医药杂志,2021,37(7):1179-1181.
薄华本,陈启助,沈晗,等.当归补血汤调控骨髓造血机理及对造血微环境的影响[J].中国新药与临床杂志,2013,32(10):824-828.
孙武,高景华,杨克新,等.当归补血汤加味方在后路腰椎内固定术后的疗效观察[J].北京中医药,2019,38(4):332-335.
许卓,初杰,崔运浩.当归补血汤煎剂对骨髓抑制小鼠EPO、TPO、GM-CSF表达的影响研究[J].中华中医药学刊,2021,39(6):229-231.
HAO Y, ZHANG Z, ZHOU F,et al. Risk factors for implant failure in reverse oblique and transverse intertrochanteric fractures treated with proximal femoral nail antirotation (PFNA) [J]. J Orthop Surg Res,2019 ,14(1):350.
张孟之,管连城,秦忠,等.当归补血汤对维甲酸致骨质疏松模型大鼠卵巢CYP24A1和ERα表达的影响[J].中药新药与临床药理,2020,31(5):502-507.
陈华梅,黄枫,申震,等.基于网络药理学探究当归补血汤治疗骨质疏松症的分子作用机制[J].中国骨质疏松杂志,2021,27(4):526-532.
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